Better DNA to make more medicine.
We design the DNA switches that control how much protein a cell makes, helping biologics teams produce more from the same manufacturing footprint.
Regulatory DNA designed for your production cells.
PROTIVA designs regulatory DNA, with a current focus on promoters that control gene expression. We optimise these sequences for the production cells being used while leaving the protein-coding gene unchanged.
We work with your team to evaluate designs in the intended cells against an agreed baseline. Successful sequences can then be licensed for your programme, and the results inform the next round of design.
How we test the designs
In a CHO evaluation, selected promoters are built into expression constructs and compared with a reference design. Keeping the gene of interest and test conditions consistent lets us compare protein output and identify which promoter designs warrant further testing. Results from these experiments guide the next round of sequence design.
Our partners and supporters
We participate in OpenAI’s Rosalind programme and NVIDIA Inception.
